{"id":822,"date":"2024-12-19T02:56:32","date_gmt":"2024-12-19T02:56:32","guid":{"rendered":"https:\/\/totalhealthsolutions.bizhall.net\/?page_id=822"},"modified":"2025-02-26T01:24:40","modified_gmt":"2025-02-26T01:24:40","slug":"relapse-prevention-rds","status":"publish","type":"page","link":"https:\/\/totalhealthsolutions.org\/wp\/relapse-prevention-rds\/","title":{"rendered":"Relapse Prevention &#8211; RDS"},"content":{"rendered":"<!--themify_builder_content-->\n<div id=\"themify_builder_content-822\" data-postid=\"822\" class=\"themify_builder_content themify_builder_content-822 themify_builder tf_clear\">\n                    <div  data-lazy=\"1\" class=\"module_row themify_builder_row tb_p8bq617 tb_first tf_w\">\n                        <div class=\"row_inner col_align_top tb_col_count_1 tf_box tf_rel\">\n                        <div  data-lazy=\"1\" class=\"module_column tb-column col-full tb_eau6617 first\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_ugjc758   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <div class=\"paragraph\"><strong>\u2022 RDS, or Reward Deficiency Syndrome is caused, in part by a genetic imbalance of dopamine in your brain<\/strong><br \/><br \/><strong>\u2022 Dopamine is the neurotransmitter responsible for your feelings of happiness, overall well-being and facilitates your decision making\u00a0ability<\/strong><br \/><br \/><strong>\u2022 When there is an imbalance due to either genetics or a stressful environment, your body tries to normalize the brain reward cascade<\/strong><br \/><br \/><strong>\u2022 Dopamine imbalance can cause excessive pleasure\/reward-seeking behaviors like substance abuse, gambling, excessive sexual activity, and thrill-seeking actions<\/strong><br \/><br \/><strong>\u2022 Individuals experiencing RDS can also have unhealthy craving behaviors, and are more prone to excess sugar and fat cravings and intake; generally overeat; and are more apt to experience metabolic dysfunction<\/strong><\/div>\n<div>\u00a0<\/div>\n<div><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-826 size-full\" src=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/rds-1_orig.jpg\" alt=\"\" width=\"1000\" height=\"645\" srcset=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/rds-1_orig.jpg 1000w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/rds-1_orig-300x194.jpg 300w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/rds-1_orig-768x495.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/div>\n<div>\u00a0<\/div>    <\/div>\n<\/div>\n<!-- \/module text --><!-- module text -->\n<div  class=\"module module-text tb_t7go174   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <div class=\"paragraph\"><strong>Definition of Reward Deficiency Syndrome (RDS)<\/strong><\/div><div class=\"paragraph\"><b><br><\/b>Over 30% of the U.S. population carries a genetic predisposition that increases their susceptibility to greater consequences from stress and risk of impulsive and addictive behaviors due to low dopamine levels.&nbsp;This predisposition is known as Reward Deficiency Syndrome (RDS).<br><br>Dr. Kenneth Blum is a world renowned scientist specializing in neuropsychopharmacology and psychiatric genetics. He is one of the world\u2019s leading authorities on the subject of dopamine.&nbsp;His discovery of the \u2018reward gene\u2019 (DRD2 A1), sometimes referred to as the \u2018addiction gene\u2019, made global headlines.&nbsp;&nbsp;According to Dr. Blum, the A1 variance of the human DRD2 (addiction) gene has been associated with drug addiction, alcoholism, and other impulsive addictive behaviors.&nbsp;&nbsp;Subsequent discoveries led Dr. Blum to coin the phrases, \u201cBrain Reward Cascade\u201d and \u201cReward Deficiency Syndrome RDS\u201d.<br><br>RDS is a disorder of the neuro-chemistry of the brain, affecting over 110 million Americans. RDS is defined in SAGE Encyclopedia of Abnormal Psychology 2017.<br><br>Reward Deficiency Syndrome (RDS) involves dopamine resistance; a form of sensory deprivation of the brain\u2019s reward or pleasure mechanisms (Blum et al.2009). The syndrome occurs as a consequence of the inability to derive reward from everyday activities. Addiction is one manifestation of RDS, although RDS can be anywhere along a spectrum from mild to severe.<br><br><strong>The Basis of the RDS<\/strong><br><br>Dopamine is a foremost component of brain function and RDS (Saddoris et al. 2016), and is also the key to feelings of well-being. For example, feelings of happiness depend on excellent brain dopaminergic functioning. This is brought about by normal function of neuroanatomy chemistry that leads to the release of dopamine. Dopamine causes \u201cpleasure\u201d and reduces \u201cstress\u201d. The release of dopamine at the reward site of the brain Nucleus Accumbens (NAc) involves a complicated process of neurotransmission called the \u201cBrain Reward Cascade\u201d (BRC).<br><br>Dopamine released into the synapse results in feelings of well-being and reduced stress. But the ultimate release of dopamine involves a complicated multi-step process which not only controls dopamine release, but the quantity of dopamine released. This process of neurotransmitters, such as serotonin, endorphins, and GABA causing dopamine release has been termed the Brain Reward Cascade (BRC) by Blum and Kozlowski in 1989.<\/div>\n<div>&nbsp;<\/div>    <\/div>\n<\/div>\n<!-- \/module text --><!-- module text -->\n<div  class=\"module module-text tb_tiih932   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-829\" src=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/brain-cascade-with-top-label-w960-o_orig.jpg\" alt=\"\" width=\"500\" height=\"345\" srcset=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/brain-cascade-with-top-label-w960-o_orig.jpg 960w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/brain-cascade-with-top-label-w960-o_orig-300x207.jpg 300w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/brain-cascade-with-top-label-w960-o_orig-768x530.jpg 768w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/>The BRC plays an important role in controlling the reinforcement of natural rewards, like food and sex, as well as unnatural rewards such as drugs of abuse or gambling. Natural rewards are related to physiological satisfaction such as hunger and reproduction. Unnatural rewards are learned rewards from acquired pleasures such as hedonic sensations (Blum, et al. 2015).\u00a0Dopamine release is the\u00a0end result of stimuli such as alcohol, drugs, food, gambling\u00a0and sex. The dopamine release minimizes negative feelings and satisfies abnormal cravings for alcohol, cocaine, heroin and nicotine associated with low dopamine function (Koob, 2015).<\/p>    <\/div>\n<\/div>\n<!-- \/module text --><!-- module text -->\n<div  class=\"module module-text tb_8ne0661   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <p><strong>Why are all Addictions Classified as \u201cReward Deficiency Syndrome (RDS)?<\/strong><\/p>\n<p>Following extensive research, a new understanding arose relating dopamine release and addictive behaviors. Research has shown alcoholism acts similar to opioids, cocaine, nicotine, food and repetitive behaviors like gambling and sex addiction in dopamine homeostasis. These psychoactive drugs and certain behaviors produce a surge of dopamine in the midbrain (mesolimbic reward center) which acts as the biologic substrate for addictive behavior. Individuals who are genetically predisposed to addictions \u201ccrave\u201d this dopamine release. These individuals crave dopamine because they have a reward deficiency that constantly drives them to actions to fill this deficiency. The impact of RDS can be reduced through non-pharmacologic treatments that help minimize hypodopaminergic activity such as exercise, diet, music and safe non-stimulant nutraceutical dopaminergic agonist therapy.<\/p>    <\/div>\n<\/div>\n<!-- \/module text --><div  class=\"module themify_builder_slider_wrap tf_clearfix module-slider tb_94a95  slider-default  \" data-lazy=\"1\">\n        <div class=\"themify_builder_slider tf_carousel tf_swiper-container tf_rel tf_overflow\" data-lazy=\"1\"        data-visible=\"1\"\n        data-tab-visible=\"1\"\n        data-mob-visible=\"1\"\n        data-scroll=\"1\"\n                        data-speed=\"1\"\n        data-wrapvar=\"1\"\n        data-slider_nav=\"1\"\n        data-pager=\"1\"\n        data-effect=\"scroll\" \n        data-height=\"variable\"\n        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The science presented in this video is an accurate description of how (KB220Z) works.<\/p>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                        <\/div>\n        <\/div>\n                        <div  data-lazy=\"1\" class=\"module_row themify_builder_row tb_bnr0895 tf_w\">\n                        <div class=\"row_inner col_align_top tb_col_count_3 tf_box tf_rel\">\n                        <div  data-lazy=\"1\" class=\"module_column tb-column col3-1 tb_ycfu895 first\">\n                            <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column tb-column col3-1 tb_6usg584\">\n                    <!-- module plain text -->\n<div  class=\"module module-plain-text tb_32x1327 \" data-lazy=\"1\">\n        <div class=\"tb_text_wrap\">\n    <iframe loading=\"lazy\" width=\"800\" height=\"500\" src=\"https:\/\/www.youtube.com\/embed\/0doX0tcEBwM?si=OIdBd8qAR_053z2i\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>    <\/div>\n<\/div>\n<!-- \/module plain text -->        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column tb-column col3-1 tb_g2j8683 last\">\n                            <\/div>\n                        <\/div>\n        <\/div>\n        <\/div>\n<!--\/themify_builder_content-->","protected":false},"excerpt":{"rendered":"<p>\u2022 RDS, or Reward Deficiency Syndrome is caused, in part by a genetic imbalance of dopamine in your brain\u2022 Dopamine is the neurotransmitter responsible for your feelings of happiness, overall well-being and facilitates your decision making\u00a0ability\u2022 When there is an imbalance due to either genetics or a stressful environment, your body tries to normalize the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-822","page","type-page","status-publish","hentry","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"builder_content":"<strong>\u2022 RDS, or Reward Deficiency Syndrome is caused, in part by a genetic imbalance of dopamine in your brain<\/strong><br \/><br \/><strong>\u2022 Dopamine is the neurotransmitter responsible for your feelings of happiness, overall well-being and facilitates your decision making\u00a0ability<\/strong><br \/><br \/><strong>\u2022 When there is an imbalance due to either genetics or a stressful environment, your body tries to normalize the brain reward cascade<\/strong><br \/><br \/><strong>\u2022 Dopamine imbalance can cause excessive pleasure\/reward-seeking behaviors like substance abuse, gambling, excessive sexual activity, and thrill-seeking actions<\/strong><br \/><br \/><strong>\u2022 Individuals experiencing RDS can also have unhealthy craving behaviors, and are more prone to excess sugar and fat cravings and intake; generally overeat; and are more apt to experience metabolic dysfunction<\/strong> \u00a0 <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/rds-1_orig.jpg\" alt=\"\" width=\"1000\" height=\"645\" srcset=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/rds-1_orig.jpg 1000w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/rds-1_orig-300x194.jpg 300w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/rds-1_orig-768x495.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/> \u00a0\n<strong>Definition of Reward Deficiency Syndrome (RDS)<\/strong><b><br><\/b>Over 30% of the U.S. population carries a genetic predisposition that increases their susceptibility to greater consequences from stress and risk of impulsive and addictive behaviors due to low dopamine levels.&nbsp;This predisposition is known as Reward Deficiency Syndrome (RDS).<br><br>Dr. Kenneth Blum is a world renowned scientist specializing in neuropsychopharmacology and psychiatric genetics. He is one of the world\u2019s leading authorities on the subject of dopamine.&nbsp;His discovery of the \u2018reward gene\u2019 (DRD2 A1), sometimes referred to as the \u2018addiction gene\u2019, made global headlines.&nbsp;&nbsp;According to Dr. Blum, the A1 variance of the human DRD2 (addiction) gene has been associated with drug addiction, alcoholism, and other impulsive addictive behaviors.&nbsp;&nbsp;Subsequent discoveries led Dr. Blum to coin the phrases, \u201cBrain Reward Cascade\u201d and \u201cReward Deficiency Syndrome RDS\u201d.<br><br>RDS is a disorder of the neuro-chemistry of the brain, affecting over 110 million Americans. RDS is defined in SAGE Encyclopedia of Abnormal Psychology 2017.<br><br>Reward Deficiency Syndrome (RDS) involves dopamine resistance; a form of sensory deprivation of the brain\u2019s reward or pleasure mechanisms (Blum et al.2009). The syndrome occurs as a consequence of the inability to derive reward from everyday activities. Addiction is one manifestation of RDS, although RDS can be anywhere along a spectrum from mild to severe.<br><br><strong>The Basis of the RDS<\/strong><br><br>Dopamine is a foremost component of brain function and RDS (Saddoris et al. 2016), and is also the key to feelings of well-being. For example, feelings of happiness depend on excellent brain dopaminergic functioning. This is brought about by normal function of neuroanatomy chemistry that leads to the release of dopamine. Dopamine causes \u201cpleasure\u201d and reduces \u201cstress\u201d. The release of dopamine at the reward site of the brain Nucleus Accumbens (NAc) involves a complicated process of neurotransmission called the \u201cBrain Reward Cascade\u201d (BRC).<br><br>Dopamine released into the synapse results in feelings of well-being and reduced stress. But the ultimate release of dopamine involves a complicated multi-step process which not only controls dopamine release, but the quantity of dopamine released. This process of neurotransmitters, such as serotonin, endorphins, and GABA causing dopamine release has been termed the Brain Reward Cascade (BRC) by Blum and Kozlowski in 1989. &nbsp;\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/brain-cascade-with-top-label-w960-o_orig.jpg\" alt=\"\" width=\"500\" height=\"345\" srcset=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/brain-cascade-with-top-label-w960-o_orig.jpg 960w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/brain-cascade-with-top-label-w960-o_orig-300x207.jpg 300w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2024\/12\/brain-cascade-with-top-label-w960-o_orig-768x530.jpg 768w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/>The BRC plays an important role in controlling the reinforcement of natural rewards, like food and sex, as well as unnatural rewards such as drugs of abuse or gambling. Natural rewards are related to physiological satisfaction such as hunger and reproduction. Unnatural rewards are learned rewards from acquired pleasures such as hedonic sensations (Blum, et al. 2015).\u00a0Dopamine release is the\u00a0end result of stimuli such as alcohol, drugs, food, gambling\u00a0and sex. The dopamine release minimizes negative feelings and satisfies abnormal cravings for alcohol, cocaine, heroin and nicotine associated with low dopamine function (Koob, 2015).<\/p>\n<p><strong>Why are all Addictions Classified as \u201cReward Deficiency Syndrome (RDS)?<\/strong><\/p> <p>Following extensive research, a new understanding arose relating dopamine release and addictive behaviors. Research has shown alcoholism acts similar to opioids, cocaine, nicotine, food and repetitive behaviors like gambling and sex addiction in dopamine homeostasis. These psychoactive drugs and certain behaviors produce a surge of dopamine in the midbrain (mesolimbic reward center) which acts as the biologic substrate for addictive behavior. Individuals who are genetically predisposed to addictions \u201ccrave\u201d this dopamine release. These individuals crave dopamine because they have a reward deficiency that constantly drives them to actions to fill this deficiency. The impact of RDS can be reduced through non-pharmacologic treatments that help minimize hypodopaminergic activity such as exercise, diet, music and safe non-stimulant nutraceutical dopaminergic agonist therapy.<\/p>\n<img src=\"data:image\/svg+xml,%3Csvg%20xmlns=%27http:\/\/www.w3.org\/2000\/svg%27%20width='800'%20height='600'%20viewBox=%270%200%20800%20600%27%3E%3C\/svg%3E\" loading=\"lazy\" data-lazy=\"1\" data-tf-not-load=\"1\" style=\"background:linear-gradient(to right,#145a82 25%,#1d658e 25% 50%,#1d658e 50% 75%,#145a82 75%),linear-gradient(to right,#23759b 25%,#99f7dd 25% 50%,#26a8a4 50% 75%,#26729c 75%),linear-gradient(to right,#388ab7 25%,#3d90be 25% 50%,#3d90be 50% 75%,#388ab7 75%),linear-gradient(to right,#459dce 25%,#449ed0 25% 50%,#449ed0 50% 75%,#459dce 75%)\" decoding=\"async\" data-tf-src=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide1-800x600.png\" width=\"800\" height=\"600\" title=\"Slide1\" alt=\"Slide1\" 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https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide10.png 960w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/noscript> <img src=\"data:image\/svg+xml,%3Csvg%20xmlns=%27http:\/\/www.w3.org\/2000\/svg%27%20width='800'%20height='600'%20viewBox=%270%200%20800%20600%27%3E%3C\/svg%3E\" loading=\"lazy\" data-lazy=\"1\" data-tf-not-load=\"1\" style=\"background:linear-gradient(to right,#fcfcfc 25%,#fbfbfb 25% 50%,#fcfcfc 50% 75%,#fbfbfb 75%),linear-gradient(to right,#fdfdfd 25%,#fefefe 25% 50%,#fcfcfc 50% 75%,#fefefe 75%),linear-gradient(to right,#fbfbfb 25%,#fbfbfb 25% 50%,#fafafa 50% 75%,#fbfbfb 75%),linear-gradient(to right,#fbfbfb 25%,#fcfcfc 25% 50%,#fbfbfb 50% 75%,#fbfbfb 75%)\" decoding=\"async\" data-tf-src=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11-800x600.png\" width=\"800\" height=\"600\" title=\"Slide11\" alt=\"Slide11\" data-tf-srcset=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11-800x600.png 800w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11-300x225.png 300w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11-768x576.png 768w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11.png 960w\" data-tf-sizes=\"(max-width: 800px) 100vw, 800px\" \/><noscript><img data-tf-not-load data-no-script src=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11-800x600.png\" width=\"800\" height=\"600\" title=\"Slide11\" alt=\"Slide11\" srcset=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11-800x600.png 800w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11-300x225.png 300w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11-768x576.png 768w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide11.png 960w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/noscript> <img src=\"data:image\/svg+xml,%3Csvg%20xmlns=%27http:\/\/www.w3.org\/2000\/svg%27%20width='800'%20height='600'%20viewBox=%270%200%20800%20600%27%3E%3C\/svg%3E\" loading=\"lazy\" data-lazy=\"1\" data-tf-not-load=\"1\" style=\"background:linear-gradient(to right,#fcfcfc 25%,#fbfbfb 25% 50%,#fcfcfc 50% 75%,#fbfbfb 75%),linear-gradient(to right,#317bbd 25%,#92b968 25% 50%,#317bbd 50% 75%,#a4c658 75%),linear-gradient(to right,#a1c9f0 25%,#a4cdee 25% 50%,#a4cdee 50% 75%,#a3c6e9 75%),linear-gradient(to right,#fefefe 25%,#fdfdfd 25% 50%,#fcfcfc 50% 75%,#fefefe 75%)\" decoding=\"async\" data-tf-src=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12-800x600.png\" width=\"800\" height=\"600\" title=\"Slide12\" alt=\"Slide12\" data-tf-srcset=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12-800x600.png 800w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12-300x225.png 300w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12-768x576.png 768w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12.png 960w\" data-tf-sizes=\"(max-width: 800px) 100vw, 800px\" \/><noscript><img data-tf-not-load data-no-script src=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12-800x600.png\" width=\"800\" height=\"600\" title=\"Slide12\" alt=\"Slide12\" srcset=\"https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12-800x600.png 800w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12-300x225.png 300w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12-768x576.png 768w, https:\/\/totalhealthsolutions.org\/wp\/wp-content\/uploads\/2025\/01\/Slide12.png 960w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/noscript>\n<p><b>Watch this video below about the science of KB220Z and how it works in the brain.<\/b><\/p> <p>IMPORTANT NOTICE for Video below: Although this Video refers to Synaptamine\u2122, the liquid form of&nbsp;KB220Z; at this time, Dr. Kenneth Blum who patented&nbsp;KB220Z&nbsp;is only endorsing the nootropic supplement, Brain Reward\u2122 through Victory Nutrition International. The science presented in this video is an accurate description of how (KB220Z) works.<\/p>\n<iframe loading=\"lazy\" width=\"800\" height=\"500\" src=\"https:\/\/www.youtube.com\/embed\/0doX0tcEBwM?si=OIdBd8qAR_053z2i\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>","_links":{"self":[{"href":"https:\/\/totalhealthsolutions.org\/wp\/wp-json\/wp\/v2\/pages\/822","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/totalhealthsolutions.org\/wp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/totalhealthsolutions.org\/wp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/totalhealthsolutions.org\/wp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/totalhealthsolutions.org\/wp\/wp-json\/wp\/v2\/comments?post=822"}],"version-history":[{"count":44,"href":"https:\/\/totalhealthsolutions.org\/wp\/wp-json\/wp\/v2\/pages\/822\/revisions"}],"predecessor-version":[{"id":1050,"href":"https:\/\/totalhealthsolutions.org\/wp\/wp-json\/wp\/v2\/pages\/822\/revisions\/1050"}],"wp:attachment":[{"href":"https:\/\/totalhealthsolutions.org\/wp\/wp-json\/wp\/v2\/media?parent=822"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}